Utilizing Enamine Intermediate from BoroncatalyzedSilylative Dearomatization of Quinolinesfor Cyclic Amidine Synthesis

초록

Because of valuable biological activities, heterocyclic compounds were widely used in medicine and agriculture. In organic synthesis, cycloaddition was one of the simplest tool to furnish heterocyclic structure. According to our previous research, N-silyl enamines from borane catalyzed hydrosilylation of the Nheteroarene showed the reactivity in [3 + 2] cycloaddition with organic azides to give amidine with high performance at roon temperature. In this study, we present ultilization of N-silyl enamines as dipolarophile in cycloaddition to synthesis new heterocyclic structure.