A Case of Merkel Cell Polyomavirus-Negative Merkel Cell Carcinoma Concurrent with Squamous Cell Carcinoma

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초록

Merkel cell carcinoma (MCC), a rare cutaneous neuroendocrine carcinoma, is most common in sun-exposed areas of aged individuals. Merkel cell polyomavirus (MCPyV) is one causative agent of MCC. Cases of MCC concurrent with other skin tumors, especially squamous cell carcinoma, are rarely reported. Immunohistochemical staining is performed using antibodies to the MCPyV large-T antigen (CM2B4) only in select cases. To date, no cases of MCPyV have been reported in Korea. Here we report a case of MCC concurrent with squamous cell carcinoma in an aged man and discuss the pathogenesis of the case through CM2B4 staining. © 2023 Korean Dermatological Association. All rights reserved.

키워드

Merkel cell carcinoma; Merkel cell polyomavirus; Squamous cell carcinoma
제목
A Case of Merkel Cell Polyomavirus-Negative Merkel Cell Carcinoma Concurrent with Squamous Cell Carcinoma
저자
Lee, Kyung-Ju; An, Hye Young; Choi, Suk-Jin; Hwang, Hye Won; Lee, Seon Bok; Shin, Hyun-Tae; Shin, Jeonghyun; Choi, Gwang Seong; Byun, Ji Won
발행일
2023
유형
Article
저널명
대한피부과학회지
권
61
호
4
페이지
239 ~ 243