Activation of NAD(P)H:Quinone Oxidoreductase by Radiation or Heat Stress Potentiates the Sensitivity of Cancer Cells to Bioreductive Drug β-lapachone

LIM, BYUNG UK

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Activation of NAD(P)H:Quinone Oxidoreductase by Radiation or Heat Stress Potentiates the Sensitivity of Cancer Cells to Bioreductive Drug β-lapachone

LIM, BYUNG UK

초록

It has been known that NAD(P)H:quinone oxidoreductase (NQO1),(DT-diaphorase)activates bioreductive drugs such as mitomycin C. β-lapachone(β-lap)is a newly identified bioreductive drug.

제목: Activation of NAD(P)H:Quinone Oxidoreductase by Radiation or Heat Stress Potentiates the Sensitivity of Cancer Cells to Bioreductive Drug β-lapachone

저자: LIM, BYUNG UK

학회명: AACR-NCI EORTC International Conference Molecular Targets and Cancer Therapeutics