Synthesis of Chiral Co (Salen) Complex Immobilized H-type BEA with treated by alkaline solution

초록

The large academic and industrial interests have been focused on the stereoselective synthesis of chiral epoxides due to their versatile utility as intermediates for the preparation of bioactive molecules. Therefore, the development in the preparation methods of optically pure terminal epoxides has been one of the important targets in the asymmetric synthesis. We have synthesized homogeneous and heterogeneous chiral dinuclear complexes and demonstrated their catalytic activity and selectivity for asymmetric ring opening (ARO) of terminal epoxides with carboxylic acid as a nucleophile. In addition, H-type Beta zeolite (H-BEA-zeolite) was modified by alkaline solution to introduce mesoporosity inside the crystals, and the chiral Co(III) salen was immobilized in the mesopores to obtain the heterogenized catalysts.