Amazing Substituent Effects on the Pyridinolysis of Y-Aryl Ethyl Chlorophosphates in Acetonitrile at 35.0 oC.

초록

The mechanistic interpretation of the organo-phosphorus compounds mostly depends on the kinetic investigations recently. By analyzing Hammett and Brönsted plots, the organo-phosphorus compounds are appearing as an interesting in the field of physical organic chemistry specially by clarification of mechanistic criteria using cross-interaction constants. In the incessant of the progress of the search, we have investigated the kinetics and concern physical factors of the pyridinolysis of Y-aryl ethyl chlorophosphates in acetonitrile at 35.0oC where Y are the various substituents in substrates. The biphasic Hammett plots indicates the mechanistic alteration during the course of reaction. The deuterium kinetic isotope effects, respective activation parameters and obtained selectivity parameters were found in support of the proposed mechanistic behavior of the present system. Where we especially endeavor to introduce the frontal and backward attack of nucleophiles through the usual phenomena of nucleophilic substitution reactions and which are generally observed for the phosphate, phosphonate and phosphinic systems.