Chondroid Syringoma: A Clinical and Histopathological Study of 17 Cases

초록

Background: Chondroid syringoma (CS) is an uncommon benign neoplasm of the head and neck seen in middle-aged to elderly individuals. Histopathologically, chondroid syringoma displays nests of cuboidal epithelial cells embedded in a matrix. It is classified as both a tubular branching lumina type and a small tubular lumina type and may exhibit a wide range of differentiation and metaplastic changes in the epithelial and stromal components. Objective: To investigate the correlation between the clinical and histopathologic features of chondroid syringoma. Methods: We evaluated the electronic medical records, clinical photographs, and histopathological slides of 17 patients diagnosed with chondroid syringoma. Results: CS in the terminal hair skin tended to have larger lesions (p=0.036). Tumors in terminal hair skin demonstrated significantly more follicular differentiation (p=0.044) than uose in the vellus hair skin. CS arising on the scalp tended to have more osseous metaplasia compared to those arising on non-scalp areas (p=0.022). Conclusion: This study showed that the clinical and histopathological feamres of CS can differ depending on its location. © 2021 Korean Dermatological Association. All rights reserved.

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