폐의 유두형 선암종의 세침흡인 세포학적 소견

초록

We report a case of fine needle aspiration cytologic findings of papillary adenocarcinoma of lung occuring in a 72-year-old korean man. Radiologically, the chest CT revealed a 2 cm-diametered lobulated solitary mass in lateral segment of right middle lobe without calcification. Cytologically, smears showed high cellularity, papillary clusters and isolated tumor cells exhibiting mild nuclear pleomorphism. In clusters the tumor cells were overlapped with relatively well distinct cell borders. Some cells were a little small in size and had hyperchromatic nuclei, scanty or moderate amount of cytoplasm and indistinct small nucleoli. Others were larger in their size and had less hyperchromatic nuclei, moderate amount of cytoplasm and dictinct small nucleoli. On high power view, nuclear membrane was irregularly thick and the chromatin pattern was coarse. Scattered foamy macrophages were also noted in the background. In differential diagnosis, we considered several benign and malignant lesions including bronchioloalveolar carcinoma, sclerosing hemangioma, metastatic adenocarcinoma, hypertrophic/hyperplastic type II pneumocytes, and reactive bronchial epithelial hyperplasia. The tumor was resected. Histologically, the tumor was diagnosed as papillary adenocarcinoma