Cutaneous metastasis as an initial manifestation of pancreatic neuroendocrine carcinoma: A case report

초록

Pancreatic neuroedocrine tumors (PNETs) are rare tumors, and they account for 1-2% of all pancreatic neoplasms. Although PNETs had heterogeneous features and showed various clinical presentation, cutaneous metastasis as an initial manifestation was very rare. Herein, we reported a new case of advanced PNET on pancreas body with initial presenting a mass on buttock. The patient was a 60-year-old man. Ten months before admission, he found a small mass on left hip, but he did nothing. As time goes, the size of mass was increasing and new mass was found in left inguinal area. CT scan detected not only 10cm sized of buttock mass and 7cm sized of inguinal lymph node but also huge mass on pancreatic body and tail. Initially, we thought the pancreatic cancer with cutaneous metastasis and excised buttock and inguinal masses for relief of symptom. However, pathology revealed that the masses were metastases of neuroendocrine carcinoma. Then patient was undergone total pancreatectomy and total gasterectomy 3 weeks after 1st operation. The patient was discharged and scheduled to receive the chemotherapy and radiotherapy.