Construction of high-density tissue microarrays at low cost by using self-made manual microarray kits and recipient paraffin blocks

초록

Background: The advance of tissue microarray (TMA) has enabled simultaneous in situ analysis of biomarker expression in a very large numbers of archived pathology specimens. However, relatively high cost for TMA construction may hamper many researchers from using this essential tool of modern pathology research. We discuss methods to make self-made TMA kits and self-made recipient blocks for manual construction of high-density TMAs at low cost.