Organic functionalization of silica-based mesoporous materials for chromatographic separations

초록

Mesoporous organic-inorganic hybrid MCM-41 was prepared using 1,2-bis-(trimethoxysilyl)ethane as a precursor. In addition,pure silica based MCM-41 was prepared and organically functionalized using Grignard reagents post- synthetically............................................ ......................................................... Potential application of these material for HPLC separation was evaluated both in normal and reverse phase mode for a series of organic feed mixtures.