Radiation-induced activation of NQO1 potentiates the cytotoxicity of bio-reductive drugs

초록

NAD(P)H:Quinone Oxidoreductase(NQO1) has been known to play cardinal role in the activation of bio-reductive anti-cancer drugs such as mitomycin C, tirapazamine, EO9 and RHI.

제목
Radiation-induced activation of NQO1 potentiates the cytotoxicity of bio-reductive drugs
저자
PARK HEON JOO
학회명
Radiation Research Society