Biomimetic Oxidative N-Debenzylation of Dibenzylamines

초록

Several benzylsubstitutedbenzylamines undergo oxidative debenzylations by cytochrome P450, FeIIITPPCl/PhIO, lead tetraacetate, and horseradish peroxidase. Relative rates (kY/kH) and kinetic isotope effects (kH/kD) were measured. The data can be interpreted in terms of electron transfer followed by hydrogen atom transfer.