Association Between Complications of Pregnancy and First Trimester Maternal Serum PAPP-A, Serum Free β-HCG and Nuchal Translucency

초록

Objectives: To investigate whether PAPP-A, free β-hCG and nuchal translucency at the first trimester screening for trisomy 21 might detect women at high risk for adverse pregnancy outcomes. Results: Patients with free β-hCG were associated with Large for Gestational Age, and patients with NT were associated with Gestational 으. No statistically significant differences were noted for other adverse outcomes. Conclusions: At 10-14 weeks gestation, low maternal serum free β-hCG levels are associated with large for gestational Age, and low NT are associated with Gestational DM. Fetoplacental products in the first trimester do not prove to be useful as a screening tool for predicting pregnancy complications.