Accuracy of PET-CT in Postoperative Gastric Cancer Compared with Contrast-enhanced CT

초록

목적:To compare diagnostic accuracy of attenuation-corrected positron emission tomography (PET) with fused PET and contrast-enhanced computed tomography (CT) in the postoperative patients who suspected recurrence of gastric cancer. 방법:Twelve patients who had underwent subtotal or total gastrectomies due to gastric cancer were enrolled in this retrospective study. Mean postoperative date was 818 days (range, 104 – 2144 days). Within 1 month, both PET-CT and contrast-enhanced abdomen-and-pevis CT were performed in all the patients to assess tumor recurrence. Comparison was performed on a lesion-by-lesion basis. Twelve sites limited within abdomen and pelvis were evaluated in each patient (that is, anastomosis, regional lymph node, distant lymph node, jejunum, ileum, colon, rectal shelf, omentum, peritoneum, mesentery, vertebra, and pelvic bone). Sensitivity, specificity, positive and negative predictive value, and accuracy in PET-CT and CT alone were evaluated on the basis of follow-up and histopathologic findings. 결과:A total of 144 foci in abdomial and pelvis were assessed. Nineteen recurrent lesion were confirmed by follow-up (n = 5 patients) or surgery (n = 7 patients). The sensitivity, specificity, postive predictive value, negative predictive value, and accuracy of PET-CT and contrast-enhanced CT alone were 79% vs 32%, 99% vs 98%, 94% vs 67%, 97% vs 90%, and 97% vs 89%, respectively. 결론: PET-CT is more accurate than contrast-enhanced CT alone in the detection of recurrent gastric cancer and has the clear potential to affect patient care.