Estimation of world seroprevalence of SARS-CoV-2 antibodies

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초록

In this paper, we estimate the seroprevalence against COVID-19 by country and derive the seroprevalence over the world. To estimate seroprevalence among adults, we use serological surveys (also called the serosurveys) conducted within each country. When the serosurveys are incorporated to estimate world seroprevalence, there are two issues. First, there are countries in which a serological survey has not been conducted. Second, the sample collection dates differ from country to country. We attempt to tackle these problems using the vaccination data, confirmed cases data, and national statistics. We construct Bayesian models to estimate the numbers of people who have antibodies produced by infection or vaccination separately. For the number of people with antibodies due to infection, we develop a hierarchical model for combining the information included in both confirmed cases data and national statistics. At the same time, we propose regression models to estimate missing values in the vaccination data. As of 31st of July 2021, using the proposed methods, we obtain the 95% credible interval of the world seroprevalence as [35.5%,56.8%].

키워드

Bayesian modelhierarchical modelSARS-CoV-2 antibodiesvaccinationworld seroprevalence
제목
Estimation of world seroprevalence of SARS-CoV-2 antibodies
저자
Lee, KwangminKim, SeongminJo, SeongilLee, Jaeyong
DOI
10.1080/02664763.2024.2335569
발행일
2024-11-17
유형
Article
저널명
Journal of Applied Statistics
51
15
페이지
3039 ~ 3058