신낭종과 신세포암의 H MR Spectroscopy의 소견의 비교연구

초록

Purpost: The purpose of this study was to investigate differential features of renal cyst and renal cell carcinoma(RCC) with in vivo H MR spectroscopy(MRS). Materials and Methods: In vivo H MRS was performed is 5 renal cysts and 7 RCCs. MRS was performed with a 1.5T unit using localized proton STEAM sequence. The body coil was used as a receiver coil and no controlled respiration was undertaken during the examinations. The parameters used were: TR=3000ms, TE=30ms, number of scans=128, and on NEX. An ROI voxel of 1-8(31-32)3cmwas placed on center of cyst or RCC. We analyzed the patterns of MR spectrums of renal cyst and RCC by recognizing lipid peak ( 1.3ppm) and protein peaks(2-4ppm). We measured area of lipid peak, protein peaks and water lipid/water, proteins/water and lipid/proteins. Particular attention was given to identify differences in lipid/protein peak ratio between renal cyst and RCC. Results: Lipid peaks were the most prominent peaks in 4 of 5 renal cysts and of 7 RCCs. Ptein peak was the most prominent peak in 1 RCC. There were no peak in 1 cyst and 2 RCCs. Lipid/water peak area ratio of renal cyst and RCC were 0.00002352 0.00005049(cyst) and 0.00000029 0.00000025(RCC). Protein/water ratio were 0.00000336 0.00000653(cyst) and 0.00000066 0.00000044(RCC). Lipid/protein ratio were 3.43 3.78(cyst) and 0.47 0.21(RCC). Conclusion: The result of this study showed that there were some differences in the spectral patterns of H MRS in renal cyst and RCC, and renal cyst contained larger amount of lipid and protein than RCC. Knowledge of these, spectral differences may provide scientific for H MRS as new non-invasive diagnostic tool of renal cyst and RCC.