Value of Plain Bone X-Ray and Blood Chemistry for Detection of Vascular Calcification (VC) of Patients on Different Dialysis Modalities

초록

[SA-PO2162] Value of Plain Bone X-Ray and Blood Chemistry for Detection of Vascular Calcification (VC) of Patients on Different Dialysis Modalities Moon-Jae Kim, Seoung Woo Lee, Woo Chul Joo, Joon Ho Song. Kidney Center, Inha University Hospital, Incheon City, Korea 10:00 AM - 2:30 PM Purpose: To evaluate detection for vascular calcification (VC) of patients between hemodialysis(HD) and peritoneal dialysis(PD) with plain radilologic bone series and blood chemistry. Methods: VC was assessed using plain X-ray on L-spine, pelvis and hand in 51 HD and 74 PD patients who used calcium-based phsophate binder more than 5 years. Calcification scoring proposed by Kauppila and Adragao were used to evaluate the presence of VC in abdominal aorta, iliac and femoral, radial and digital arteries. We analyzed the difference in VC according to dialysis modality. Results: One hundred and twenty five patients were included. Mean age were 57+13, 54+13 years in HD and PD groups respectively. Dialysis duration was 6.4+3.4 years in HD, 5.6+2.3 years in PD. Diabetics (DM) were 29(56.9%) in HD and 25(33.3%) in PD. Calcification scores of lumbar was correlated with scores of pelvis(r=0.561, p<0.001) and of hand(r=0.236, p=0.008). In HD patients, lumber score was correlated with age (r=0.378, p=0.006) and albumin(r= -0.284, p=0.046). In PD patients, lumbar score was correlated with age. However, HD showed more VC of digital bone(37.3 vs. 17.6%, p=0.013) and had higher scores than PD ( 0.9+1.3 vs. 0.5+1.0, p=0.054). Diabetics and male were also high scores of VC on abdominal arteries in both groups. Daily calcium load of phasphate binder and presence of residual renal function were similar between two modailties. But serum creatinine, HDL-cholesterol and iPTH levels were significantly lower in patients with low scores of VC in radial and digital arteries in both groups. Conclusion: There seems to be significant difference in the location and degree of VC according to dialysis modality. HD