Analysis of growth and gene expression of C. elegans exposed to low-frequency mechanical vibration during early developmental period

초록

Vibration is an important physical stimulus to living organisms. Previous studies have focused on the mechanical vibration effects on cells, as either a factor of promotion or inhibition. However, there have been few studies on this effect at the organism scale. Some studies have shown only the behavior response of a model organism, such as C. elegans, to vibration. In this study, we demonstrate the vibration effect on the embryonic period of C. elegans. Vibration was found to affect growth promotion and gene expression. Furthermore, we obtained results for the wild-type (N2) and sur-5::gfp mutant of C. elegans. We expect this investigation to provide a foundation for various future vibration effect studies on C. elegans. © 2019 The Korean Society of Mechanical Engineers.

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