INJECTION OF MINIMAL-DOSE INTRAVENOUS HEPARIN BEFORE MECHANICAL THROMBECTOMY DID NOTAFFECT THE INCIDENCE OF SYMPTOMATIC HEMORRHAGIC CONVERSION OR DISTAL CLOT MIGRATION.

초록

Background and aims: Previous studies indicated the usual dose heparin(5000 IU bolus followed by 500~1250 IU/h) during mechanical thrombectomy is associated with an increased risk of hemorrhagic transformation without beneficial effect. East Asians are known to have a higher risk of bleeding compared to other races, and they often take lower doses of antithrombotics. However, role of minimal-dose heparin as an adjuvant treatment before thrombectomy in East Asians remains unclear. Methods: We enrolled the patients who underwent mechanical thrombectomy from the Inha University Hospital Stroke Prospective Registry and compared clinical findings between patients who received heparin bfore thrombectomy and those who did not.