Impact of Final Kissing Balloon Inflation after Simple Stent Implantation for the Treatment of Non-left Main True Coronary Bifurcation Lesions in Patients with Acute Coronary Syndrome

초록

Objectives We sought to evaluate the impact of final kissing balloon inflation (FKBI) after simple stent implantation for the treatment of non-left main true coronary bifurcation lesions in patients with acute coronary syndrome (ACS). Background Whether FKBI should be mandatory after simple stent implantation for the treatment of coronary bifurcation lesion is controversial. Besides, ACS patients who have undergone bifurcation percutaneous coronary interventionwith simple stent implantation may experience worse prognosis compared to stable angina pectoris patients. Methods Two hundred and fifty oneeligiblepatients (67.7% male, mean age 61.7±10.4 years) were enrolled.The study population was divided into two groups according to the performance of FKBI. The primary end pointswere major adverse cardiac event (MACE); target lesion revascularization (TLR), non-fatal myocardial infarction (MI) and cardiac death during the follow-up period. Results Over a mean follow-up period of 3.0±1.9 years, there were 29 MACEs (10 TLR, 6 non-fatal MI, and 13 cardiac deaths),representing an event rate of 11.6%. Kaplan-Meier survival analysis revealed that FBKI group hadfavorable outcome compared to non-FKBI group with regard to hard events (p=0.010) as well as composite MACEs (p=0.008). In multivariable analysis, FKBI was a significant predictor of composite MACEs[hazard ratio 0.398 (95% confidence interval 0.190–0.836, p=0.015)] and hard events [hazard ratio 0.325 (95% confidence interval 0.130–0.811, p=0.016)]. Conclusions In terms of prognosis, performing FKBI after simple stent implantation for the treatment of non-left main true coronary bifurcation lesions may be mandatory inACS patients.