Effects of modified ultrafiltration on right heart function in adult patients undergoing valvular heart surgery

초록

Introduction : Modified ultrafiltration has been demonstrated to have beneficial effects in children undergoing cardiac surgery with cardiopulmonary bypass. In adults, the haemodynamic effects of MUF are little known. The purpose of this investigation was to evaluate the effects of MUF on right ventricular function and systemic haemodynamics in adult patients undergoing valvular heart surgery. Method : Thirty patients scheduled for elective mitral valvular surgery were randomized into either Ultrafiltration of CPB for 20 minutes. Haemodynamic variables including right ventricular ejection fraction b thermodilution technique and haematocrit were measured before anaes thesia induction, just after termination of CPB, after completion of MUF in U group, and 20 minute after T2 in C group and after sternal closure. In the ICU, the same measurements were performed at postoperative 6 and 12 horus. Statistical evaluations were performed with Mann-Whitney U-test and Wilcoxon signed rank test. Results : Total volume filtered during MUF in U group was 1033±305㎖. There was no significant difference in total amount of fluid infused and urine output during operation between C and U group. After MUF, RVEF and haematocrit increased in the U group, compared to the values.