Longterm clinical impact of sinus rhythm restoration in atrial fibrillation patients with heart failure with midranged ejection fraction

초록

Background: It has been recently reported that a lowering atrial fibrillation (AF) burden in patients coexisting atrial fibrillation and heart failure with reduced ejection fraction was associated with lower rates of death from any cause and lower rates of hospitalization for heart failure. However, it is unclear whether sinus rhythm restoration is associated with all cause mortality or hospital admission in AF patients with heart failure with midranged ejection fraction (HFmrEF). Purpose: The aim of our study was to determine the impact of sinus rhythm (SR) restoration by antiarrhythmic drugs (AADs) on mortality or hospitalization in AF patients with HFmrEF during longterm followup.