The risk factors for bronchial hyperresponsiveness in children with allergic rhinitis

초록

Purpose: Previous studies have demonstrated that bronchial hyperresponsiveness(BHR) is observed in a proportion of patients with allergic rhinitis. Thus, this study was performed to investigate the incidence of BHR and the risk factors of BHR in Korean children with allergic rhinitis. Methods: Thirty children with perennial allergic rhinitis were evaluated with total IgE, blood eosinophil count and serum concentration of ECP. They also underwent spirometry, methacholine provocation test, and skin prick test. Results: The prevalence of BHR was 20%. The level of total IgE was not different between BHR-positive and BHR-negative children with AR. The concentration of blood eosinophil and serum ECP were significantly increased among BHR-positive subjects. The skin test reactivity to other allergen except house dust mites ,…. Conclusion: The BHR was significantly associated with the concentration of blood eosinophil and serum ECP. These findings suggest that