Fluid-structure interaction analysis for dynamic intraocular pressure monitoring in the human eye

초록

This paper presents the preliminary study on the fluid-structure interaction (FSI) analysis of dynamic intraocular pressure (TOP) in the human eye. Because Glaucoma, a chronic disease of the optic nerve, can lead to blindness, the monitoring of IOP through tonometry is essential to prevent the increase of IOP. One of the most common tonometry methods to estimate IOP includes measuring corneal deflection by using either a direct contact or non-contact (e.g. air puff) impact force. Then, the dynamic characteristics of IOP should be investigated for improved correlation to IOP monitoring systems. In this paper, we develop a finite element model of a human eye as a spherically shaped structure filled with inviscid pressurized fluid to solve a problem of a fluid-coupled structural interaction of eye. The structural shape effects due to change in IOP are examined, and the proposed model is modified to further examine by including the mechano-luminescence (ML) membrane acting as IOP monitoring element. The effect of biomechanical parameters such as the ML membrane thickness is investigated based on the air puffy type applanation tonometry models.

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