폐의 점액성암종의 조직학적 면역조직화학적 염색소견

초록

A 48-year-old woman was first seen at our hospital 1997 for evaulation of abnormal chest radiographic finding. At that time, CT scan demonstrated a 2.5cm sized soft tissue lesion in apical segment of right upper lobe. Thrans bronchial lung biopsy was failed. She revisited in 2003 and CT scan revealed a slightly increased soft tissue mass with lobulated contour in the same location. A singlr lobulated solid mass showing pale yellow mucoid cut surface was seen. Microscopically, the tumor showed exuberant production of mucin. Careful serach demonstrated very small amount of tall columanr, mucin-producing epithelium with hyperchromatic nuclei focally lining alveoli and forming glands. The neoplastic cells were positive for CK20, EMA, CEA, B72.3 and p53 protein. Our case demonstrated similar immunohistochemical findings to mucinous bronchioloalveolar carcinoma therefore thia tumor may represent a variant of brochioloalveolar carcinoma.