갑상선질환에서 골건강 평가 및 관리 권고안

초록

Thyroid hormones have an important physiological role in maintaining adult bone structure and strength. Therefore, thyroid dysfunction is inevitably associated with various degrees of skeletal consequences. Endogenousovert hyperthyroidism is an established cause of high bone turnover with accelerated bone loss, resulting inosteoporosis and an increased risk of fractures. Hyperthyroidism induced by thyroid stimulating hormonesuppression therapy in patients with differentiated thyroid cancer also has emerged as a contributing factor toosteoporosis and fragility fractures. While, there is lack of evidence that hypothyroidism negatively affects bonehealth. Although there is growing clinical evidence of the importance of bone health in hyperthyroidism, clinicalguidelines on how to evaluate and manage bone health in these diseases have not yet been published worldwide. The Task Force from the Korean Thyroid Association Committee of Clinical Practice Guideline has developed thisposition statement for the evaluation and management of bone health in patients with thyroid diseases,particularly focused on endogenous hyperthyroidism and thyroid stimulating hormone suppression therapyassociatedhyperthyroidism in patients with differentiated thyroid cancer.

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