방추세포형 지방육종의 세침흡인 세포학적소견

초록

Liposarcoma is the second most common soft tissue sarcoma in adulthood comprising approximately 20% of cases. Among them, spindle cell liposarcoma is an uncommon variant of well-differentiated liposarcoma. It occurs in middle-aged adults with a male predominance. It is a low-grade sarcoma capable of recurrence, differntiation, and metastasis. We report on the fine-needle aspiration cytologic findings of a well-differentiated spindle cell liposarcoma in the posterior neck from a 70-year-old male. Cytologically, moderately cellular smear predominantly composed of spindle cells. Some areas reveal fine arborising vessels and spindle cells in the myxoid background. additionally, typical spindle cells are found between mature adipocytes. Lipoblast-like cells are also present. Spindle cells are relatively bland and arranged in short fascicles. The show mild pleomorphism and a few mitoses. Cell border is inditinct and cytoplasm is scanty. The nuclei are hyperchromatic with distinct nucleoli. An excision for mass was performed. Grossly, the specimen was an ovoid shaped soft tissue mass with irregular margin, measuring 5.0x3.0x3.0cm. The cut surface was yellowish gray and myxoid. Microscopical findings were compatible with spindle cell liposarcoma. Immunhostychemically, the spindle cells were postiive for vimentin, desmin and CD34 and negative for smooth muscle actin. The atypical adipocytic cells were positive for S-100 protein.