The clinical chractersistics of factor V deficiency in 10 Korean Patients

초록

Factor V (FV) deficiency is a rare bleeding disorder associated with a spectrum of hemorrhagic symptoms, ranging from mucosa and soft tissue bleeding such as epistaxis and hemarthroses to life-threatening hemorrhages. Until now, more than 200 cases of FV deficiency have been described in literature and the prevalence is approximately 10 times more frequent in countries in Western Asia, Europe, Australia and North America than Eastern Asia. In comparison with other countries, similar bleeding episodes were noted in Korean patients with severe and moderate FV deficiency. However, life-threatening bleeding events in patient with severe FV deficiency had tendency to occur more frequently among patients in Korea than in these countries.