A giant mesenteric fibromatosis involving the ascending colon

초록

Mesenteric fibromatosis (MF) or intra-abdominal desmoid tumor is a rare proliferative fibroblastic lesion of the intestinal mesentery. It constitutes 8% of all desmoid tumors, which represent 0.03% of all neoplasm. The biologic behavior of MF is intermediate between benign fibrous neoplasms and fibrosarcomas, and locally aggressive tumor that lacks metastatic potential but the local recurrence is very common (25-50%). The MF is a very rare tumor, especially a giant tumor involving the colon wall. In addition, treatment of giant MF still remains a challenge. Treatment modalities include surgically wide excision, antiestrogen, radiotherapy, and chemotherapy though efficacy is unpredictable. The diagnosis of mesenteric fibromatosis should always be considered in mesenchymal tumors originating from the bowel wall that diffusely infiltrate the mesentery. A multidisciplinary approach is needed with long term follow up for detecting tumor recurrence.