새로운 비대칭 아릴릭 리간드의 치환과 고정화

초록

During the last decade, various enantioselective catalysts have been developed for palladium-catalyzed allylic substitution reactions. In particular, chiral phosphinooxazoli-dine ligands are one of the effective ligands in this reaction. In this study, we developed new chiral oxazolidines and immobilized these ligands on the support. Designing a ligand for allylic substitution which can provide asymmetric induction will include the incorporation of two different donor atoms. Chral phosphinoalcohols and (2-diphenylphosphino)benzalehyde. so, we have synthesized new oxazolidines using aminoalcochols containing sufur atom(methinol, s-methyl cysteinol, s-benzyl cysteinol) and various aldehydes(2-thiophenecarbxaldehyde, 2-pyridinealdehyde).