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Lateral flow assay for the detection of norovirus using peptide-coated gold nanoparticles
- You, Taeyeong;
- Jeong, Woojin;
- Kim, Sun Min;
- Jeon, Tae-Joon
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0초록
Norovirus is notorious for foodborne illnesses all over the world. Herein, we introduce a lateral flow assay(LFA) using peptide-functionalized gold nanoparticles(AuNPs) for the detection of norovirus virus-like particles. Anti-norovirus peptides as probes were conjugated to AuNPs and its detection performance was evaluated. As a result, the visual limit of detection with NoroBP-nonfoul-(FlexL)2 in LFA reaches as low as 107 particles/ml. The results indicate that NoroBP-nonfoul-(FlexL)2 has a potential as a novel type of LFA system for easy-to-use, cost-effective, and point-of-care diagnostic platform. © 2020 CBMS-0001
키워드
Affinity peptide; Colorimetric; Lateral flow assay; Norovirus detection
- 제목
- Lateral flow assay for the detection of norovirus using peptide-coated gold nanoparticles
- 저자
- You, Taeyeong; Jeong, Woojin; Kim, Sun Min; Jeon, Tae-Joon
- 발행일
- 2020
- 유형
- Conference paper
- 저널명
- MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
- 페이지
- 1218 ~ 1219