Pulmonary Myopericytoma: A Case Report

초록

Myopericytoma is a recently described distinct neoplasm composed of perivascular myoid tumor cells. These tumors most commonly located in dermal or subcutaneous tissues of the extremities. Myopericytoma arising from lung is extremely rare and only one case of pulmonary myopericytoma had been reported recently. We report an unusual pulmonary myopericytoma in a 53-yearold man. A solitary pulmonary nodule was detected radiologically during his health checkup. The percutaneous needle biopsy revealed proliferation of uniform spindle to round cells with vimentin and SMA positivity. The patient underwent a subsequent lobectomy of the lung. Grossly, the 2.0×1.8 cm nodule was well circumscribed and gray tan. Microscopic examination showed a spindle cell neoplasm composed of plump spindle to round cells with eosinophilic or amphophilic cytoplasm. Rich thin-walled blood vessels with a henangiopericytoma-like pattern were also noted. Characteristically the tumor cells distributed perivascular area with concentric growth pattern. Pleomorphic cells were seen occasionally. Mitotic figures was noted up to 3 per 50 high power field. Immunohistochemical stains were positive for vimentin, SMA, and negative for CD34, cytokeratin, desmin, S-100, EMA, HMB45, and Bcl-2. Therefore, the final diagnosis was myopericytoma. Key Words: Myopericytoma, Lung ‘