Caffeine Molecular Imprinted Microgel Spheres by Precipitaion Polymerizaton

초록

Imprinted uniform microgel spheres were prepared by precipitation polymerization. Acetonitrile was used as porogen with MAA as the monomer, EGDMA as the crosslinker and caffeine as the imprinting molecule. Comparison of caffeine adsorption on molecular imprinted and blank microgel spheres was made. Langmuir model was used to fit the adsorption data. It was found that the caffeine imprinted microgel spheres show specific binding sites to the target molecules. Binding study of caffeine on imprinted microgel spheres was made by Scatchard analysis. This microgel spheres can be useful affinity adsorbents in further applications.