Differential antimicrobial activity of Artemisia mongolia Fischer extract against pathogenic bacteria and Lactobacillus spp.

초록

Antimicrobial substances originated from plants have been investigated to obtain natural sources of antimicrobial activity1). In previous reports, the extracts which were extracted with solvents such as acetone, ethanol, and methanol from Artemisia mongolia Fishcer showed a selective antimicrobial activity against various microorganisms2). In this study we performed antimicrobial activity test by using the extract of A. Mongolia Fishcher on pathogenic bacteria such as Esherichia coli O157 H:7, Salmonella typhimurium and Listeria monocytogenes along with lactic acid bacteria, Lactobacillus spp. isolated from human vagina to determine the possibility of using the extract as vaginal antiseptics. By using broth dilution method, the methanol extract inhibited the growth of pathogenic bacteria effectively while did not inhibit the growth of Lactobacillus spp. examined. Subsequently, we suggest that the extract of A. mongolia Fishcers could be used as vaginal antiseptics. Further study are under way to determine the mechanism of differential antimicrobial activity of A. mongolia Fischer extract against pathogenic bacteria and Lactobacillus spp..