펄스 레이저 가공에 의한 마이크로 그루브 패턴이 골 세포 유착에 미치는 영향 분석

Analysis of the Effect of Micro-groove Patterns on Osseointegration using Pulsed Laser Processing
  • 하석재
  • 성시명
  • 김혜진

초록

As the demand for biomaterials and medical devices increases due to advancements in medical technology and the rising average lifespan of the population, the importance of surface treatment technology for biometallic materials used in orthopedic implants is highlighted. Achieving stable mechanical attachment between the implant and human bone, specifically bone cell adhesion, is crucial. Without proper adhesion, issues such as inflammation and reduced load-bearing capacity can occur, leading to the need for implant reimplantation. Therefore, this paper focuses on creating a micro-groove pattern using a pulsed nanosecond laser on the surface of a titanium alloy (Ti6Al4V), a biometallic material, to promote cell adhesion. To evaluate the effectiveness of the pattern in enhancing cell adhesion, MG-63 osteoblasts were cultured on the micro-groove patterned surface, and their adhesion and morphological changes were analyzed. This study confirms the potential of laser processing as a surface treatment method for biometallic materials.

키워드

Cell cultureCell morphologyLaser surface texturingTitaniumOsseointegration
제목
펄스 레이저 가공에 의한 마이크로 그루브 패턴이 골 세포 유착에 미치는 영향 분석
제목 (타언어)
Analysis of the Effect of Micro-groove Patterns on Osseointegration using Pulsed Laser Processing
저자
하석재성시명김혜진
DOI
10.22847/ksdme.18.3.202409.005
발행일
2024-09
유형
Y
저널명
Design & Manufacturing
18
3
페이지
30 ~ 36