Uncontrolled hypertension is the most common trigger factor of posterior reversible encephalopathy syndrome in patients with chronic kidney disease

초록

Posterior reversible encephalopathy syndrome (PRES) is characterized by a clinical and radiological entity with rapid onset of seizures, headache, altered consciousness and visual disturbance with neuroimaging findings of reversible vasogenic subcortical edema. It is postulated to have a pathogenesis similar to hypertensive encephalopathy, although correlation with elevated blood pressure has not been demonstrated in chronic kidney disease(CKD).Despite the diverse initial trigger factors of PRES, uncontolled hypertension seems to be the common pathogenic pathway for PRES in CKD. For prevention of PRES in CKD patients, more intensive antihypertensive drugs should be prescribed if blood pressure is not under control.