THE PREVALENCE OF CHRONIC KIDNEY DISEASE AND THE PREDICTORS OF DECREASED KIDNEY FUNCTION IN HYPERTENSIVE PATIENTS IN WESTERN SEASIDE OF KOREA

초록

Background: Hypertension (HT) is one of treatment targets for the progression of chronic kidney disease. HT has been known to play an important role in progression of chronic kidney disease (CKD). However, limited data are available in HT patients enjoying very salty food. We evaluated the prevalence of CKD and the predictors of decreased kidney function (DKF) in HT patients in living in seaside of Korea. Methods : We retrospectively analyzed the medical records of outpatients with HT in Inha University hospital in located in seaport of western part of Korea. DKF was defined as annual loss of estimated glomerular filtration rate (eGFR) more than 10% of baseline eGFR. Results : The prevalence of CKD was 51% in 981 total participants. In HT patients without CKD (NCKD-HT), the incidence of DKF was 46.2%. The incidence of DKF in HT patients with CKD (CKD-HT) was 40.8%. Age was only baseline risk factor of DKF in NCKD-HT group. In multifactorial analysis, history of diabetes mellitus (odds ratio [OR], 2.99; 95% Confidence Interval [CI], 1.88±4.78), hemoglobin levels (OR, 0.86; 95% CI, 0.76±0.98), proteinuria (OR, 1.86; 95% CI, 1.16±2.98), and hematuria (OR, 1.62; 95% CI, 1.02±2.58) were related to DKF in CKD-HT group. Conclusion :We suggest that the prevalence of CKD in HT patients is high and DKF is frequent in both NCKD-HT and CKD-HT groups living in the seaside area of Korea . The pattern of the predictors of DKF shows the difference between the two groups. Especially diabetes, abnormal urinalysis, and anemia are strongly associated with DKF in CKD-HT group.