Evidence-based Korean guidelines for the clinical management of multiple myeloma: addressing 12 key clinical questions

  • Jung, Sung-Hoon
  • Koh, Youngil
  • Kim, Min Kyoung
  • Kim, Jin Seok
  • Moon, Joon Ho
  • ... Cho, Jinhyun
  • 외 38명
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초록

Multiple myeloma (MM), a hematological malignancy, is characterized by malignant plasma cell proliferation in the bone marrow. Recent treatment advances have significantly improved patient outcomes associated with MM. In this study, we aimed to develop comprehensive, evidence-based guidelines for the diagnosis, prognosis, and treatment of MM. We identified 12 key clinical questions essential for MM management, guiding the extensive literature review and meta-analysis of the study. Our guidelines provide evidence-based recommendations by integrating patient preferences with survey data. These recommendations include current and emerging diagnostic tools, therapeutic agents, and treatment strategies. By prioritizing a patient-centered approach and rigorous data analysis, these guidelines were developed to enhance MM management, both in Korea and globally.

키워드

Multiple myelomaGuidelinesMeta-analysisTreatmentPrognosisSTEM-CELL TRANSPLANTATIONMINIMAL RESIDUAL DISEASELENALIDOMIDE PLUS DEXAMETHASONEPREVIOUSLY UNTREATED PATIENTSPROGRESSION-FREE SURVIVALBONE-MARROW INVOLVEMENTHIGH-DOSE DEXAMETHASONEOPEN-LABELZOLEDRONIC ACIDDOUBLE-BLIND
제목
Evidence-based Korean guidelines for the clinical management of multiple myeloma: addressing 12 key clinical questions
저자
Jung, Sung-HoonKoh, YoungilKim, Min KyoungKim, Jin SeokMoon, Joon HoMin, Chang-KiYoon, Dok HyunYoon, Sung-SooLee, Je-JungHong, Chae MoonKang, Ka-WonKwon, JihyunKim, Kyoung HaKim, Dae SikKim, Sung YongKim, Sung-HyunKim, Yu RiDo, Young RokMun, Yeung-ChulPark, Sung-SooPark, Young HoonShin, Ho JinEom, Hyeon-SeokYoon, Sang EunHwang, Sang MeeLee, Won SikLee, Myung-wonYi, Jun HoLee, Ji YunLee, Ji HyunLee, Ho SupLim, Sung-NamLim, JihyangYhim, Ho-YoungChang, Yoon HwanJo, Jae-CheolCho, JinhyunCho, HyungwooChoi, Yoon SeokCho, Hee jeongAhn, AriChoi, Jong HanKim, Hyun JungKim, Kihyun
DOI
10.1007/s44313-025-00055-9
발행일
2025-12
유형
Review
저널명
Blood Research
60
1