Phytochemicals

초록

Methods for living longer and healthier have attracted the attention of both the public and researchers. One interesting method for inducing a longer and healthier life is dietary supplementation with plant-derived phytochemicals. Phytochemicals are secondary metabolites of plants that function to protect the plant from environmental stresses and provide beneficial effects on the health of animals that consume them. Those effects are the result of the phytochemical’s biological activities including antioxidation, antiinflammation, and cytotoxic activities. Many phytochemicals are reported to have beneficial effects on age-related diseases including cancer, diabetes, immune disease, inflammation, and neurodegenerative diseases. In addition, phytochemicals have been reported to extend the lifespan of experimental animals including yeast, worms, flies, fish, and mice. In this chapter, we summarize and review phytochemicals, such as resveratrol, curcumin, catechin, and quercetin, that have been widely reported to have life-extending effects, and we discuss the putative underlying mechanisms related to the prolongevity effect of phytochemicals. © 2019 Elsevier Inc. All rights reserved.

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